[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"$fyWvbWtPHJ7vJ9r7U6TMQIf4yyZxZn0ZLHtq--LOI2Yc":3},{"code":4,"msg":5,"data":6},200,"操作成功",{"id":7,"title":8,"content":9,"digest":10,"source":10,"coverPath":11,"thumbsCoverPath":12,"isTop":13,"isShow":14,"baseClick":13,"clickCount":15,"createTime":16,"typeId":17,"isNewest":18,"newsInfoTypeRespVo":19,"voiceUrl":22,"voiceSize":23,"taskId":24,"releaseTime":25,"titleEn":26,"contentEn":27,"voiceUrlEn":28,"taskIdEn":29,"voiceSizeEn":30},1770,"我国研发硅藻微米机器人     精准“狙击”脑胶质瘤","\u003Cp>\u003Cstrong style=\"font-size: 18px;\">近日，我国在脑胶质瘤精准治疗领域取得重要突破，中国科学院沈阳自动化研究所联合中国医科大学附属盛京医院，成功研发出硅藻微米机器人，可实现对脑胶质瘤的精准靶向杀伤，相关研究成果发表于《生物设计与制造》，为这一医学难题的解决提供了全新思路。\u003C\u002Fstrong>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"font-size: 18px;\"> \u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"font-size: 18px;\">脑胶质瘤病灶区域复杂、药物递送难度大，是医学界公认的治疗难题。此次研发的硅藻微米机器人开创性以自然界单细胞生物硅藻为结构母体，其天然的多孔二氧化硅硅藻壳坚硬透明，成为药物装载与靶向递送的天然容器，且全程无需外源性载药，从根源上规避了靶向递送中的药物泄漏风险，大幅减少对正常组织和细胞的损伤。\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"font-size: 18px;\"> \u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"font-size: 18px;\">科研团队通过人工智能算法，赋予机器人自主闭环运动能力，在外部磁场精准控制下，微米级的机器人可穿越组织狭窄缝隙，沿预设轨迹精准抵达胶质瘤病灶区域。与传统技术不同，该机器人直接利用硅藻细胞内的内源性叶绿素作为光敏剂，抵达病灶后，经激光激活即可产生光动力效应，实现对癌细胞的精准杀伤。\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"font-size: 18px;\"> \u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"font-size: 18px;\">动物实验结果验证了技术的有效性与安全性，激光激活后的硅藻机器人对原代胶质瘤细胞杀伤效果显著，使癌细胞存活率降至 19.5%，且未产生明显全身毒性，生物相容性良好。研究人员表示，未来该成果有望与术中导航、体内远距离递送等技术结合，进一步提升靶向性与治疗效果，为脑胶质母细胞瘤的临床治疗打造全新的自动化解决方案。\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"font-size: 18px;\"> \u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(187, 187, 187);\">【新闻来源】人民网     \u003C\u002Fspan>\u003Ca href=\"http:\u002F\u002Ffinance.people.com.cn\u002Fn1\u002F2026\u002F0316\u002Fc1004-40682553.html\" rel=\"noopener noreferrer\" target=\"_blank\" style=\"color: rgb(187, 187, 187);\">\u003Cu>http:\u002F\u002Ffinance.people.com.cn\u002Fn1\u002F2026\u002F0316\u002Fc1004-40682553.html\u003C\u002Fu>\u003C\u002Fa>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(187, 187, 187);\">（本网转发此文章，旨在为读者提供更多的信息资讯，所涉内容不构成投资、消费建议。文章事实如有疑问，请与有关方核实，文章观点非本网观点，仅供读者参考。）\u003C\u002Fspan>\u003C\u002Fp>","","https:\u002F\u002Fimage.51xinwei.com\u002F2026\u002F03\u002F6e6558780db943a48f82b67571b45082\u002F超限探索.jpg","https:\u002F\u002Fimage.51xinwei.com\u002F2026\u002F03\u002Fthumbs\u002F6e6558780db943a48f82b67571b45082\u002F超限探索.jpg",0,1,33,"2026-03-20 16:08",2,false,{"id":17,"name":20,"enName":21},"芯位视野","Xinwei Vision","https:\u002F\u002Fxinwei-dev-test.oss-cn-shenzhen.aliyuncs.com\u002Fintelligent\u002Faudio%3A1ddcbe83-78f5-4846-a639-4b62cc35e7f4%3A0.wav?Expires=1773998973&OSSAccessKeyId=LTAI5tNvY2RkKjZw4LLWsrPK&Signature=4UAnqaF9C3IhqWh4Mjiz52tATNk%3D",3334054,"1ddcbe83-78f5-4846-a639-4b62cc35e7f4","2026-03-20 16:06","China Develops Diatom Microrobots for Precise \"Sniper\" Treatment of Brain Gliomas","\u003Cp>\u003Cstrong style=\"font-size: 18px;\">Recently, China has made significant breakthroughs in the precise treatment of brain gliomas. The Shenyang Institute of Automation, Chinese Academy of Sciences, has collaborated with Shengjing Hospital, Affiliated to China Medical University, and successfully developed diatom microrobots that can precisely target and kill brain gliomas. The related research findings were published in \"Bio-Design and Manufacturing,\" providing a new approach to solving this medical challenge.\u003C\u002Fstrong>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"font-size: 18px;\"> \u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"font-size: 18px;\">The lesion areas of brain gliomas are complex, and drug delivery is difficult, making it a recognized treatment challenge in the medical field. The developed diatom microrobots use naturally occurring single-celled organisms, diatoms, as structural templates. Their naturally porous silicon dioxide diatom shells are hard and transparent, serving as natural containers for drug loading and targeted delivery. Moreover, no exogenous drugs are needed throughout the process, effectively avoiding the risk of drug leakage during targeted delivery and significantly reducing damage to normal tissues and cells.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"font-size: 18px;\"> \u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"font-size: 18px;\">The research team used artificial intelligence algorithms to give the robot autonomous closed-loop movement capabilities. Under the precise control of an external magnetic field, the micrometer-scale robots can pass through narrow tissue gaps and accurately reach the glioma lesion area along a preset trajectory. Unlike traditional techniques, the robot directly uses endogenous chlorophyll within the diatom cell as a photosensitizer. After reaching the lesion site, it can generate a photodynamic effect upon laser activation, achieving precise killing of cancer cells.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"font-size: 18px;\"> \u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"font-size: 18px;\">Animal experimental results have validated the effectiveness and safety of the technology. The diatom robots activated by laser showed significant killing effects on primary glioma cells, reducing the survival rate of cancer cells to 19.5%, with no obvious systemic toxicity and good biocompatibility. Researchers stated that in the future, this achievement could be combined with intraoperative navigation and long-distance in vivo delivery technologies, further enhancing targeting and therapeutic effects, and creating a brand-new automated solution for the clinical treatment of glioblastomas.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cbr>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"font-size: 18px;\"> \u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(187, 187, 187);\">[News Source] People's Daily     \u003C\u002Fspan>\u003Ca href=\"http:\u002F\u002Ffinance.people.com.cn\u002Fn1\u002F2026\u002F0316\u002Fc1004-40682553.html\" rel=\"noopener noreferrer\" target=\"_blank\" style=\"color: rgb(187, 187, 187);\">\u003Cu>http:\u002F\u002Ffinance.people.com.cn\u002Fn1\u002F2026\u002F0316\u002Fc1004-40682553.html\u003C\u002Fu>\u003C\u002Fa>\u003C\u002Fp>\u003Cp>\u003Cspan style=\"color: rgb(187, 187, 187);\">（This article is reprinted by this website to provide readers with more information. The content does not constitute investment or consumer advice. If there are any questions about the facts of the article, please verify with the relevant parties. The views expressed in the article are not the views of this website and are for reference only.）\u003C\u002Fspan>\u003C\u002Fp>","https:\u002F\u002Fxinwei-dev-test.oss-cn-shenzhen.aliyuncs.com\u002Fintelligent\u002Faudio%3A65a3e50b-098b-4570-be70-25feeae26723%3A0.wav?Expires=1774322313&OSSAccessKeyId=LTAI5tNvY2RkKjZw4LLWsrPK&Signature=KA4v9XJJbLFa9MoHaW1lJthSGeI%3D","65a3e50b-098b-4570-be70-25feeae26723",3117530]